Le Grand Serum
Le Grand Serum
Biologique Recherche

Le Grand Serum

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Le Grand Serum stands out as the ultimate skincare elixir, revered for its transformative effects on aging skin. With a comprehensive range of actions, this firming serum offers a complete treatment for the epidermis, effectively combating signs of aging.

Reformulated around the highly efficient Télomeractiv©, Le Grand Serum is designed to improve the stability and longevity of telomeres, crucial for preventing the irreversible signs of cell aging. This revolutionary anti-senescence active ingredient not only slows down the aging process of skin cells but also boosts collagen production, resulting in firmer, more youthful-looking skin.

This innovative formula is concentrated with 27 anti-wrinkle, antioxidant, firming, and regenerating ingredients, ensuring comprehensive protection for the skin throughout the day. The result? Visibly reduced wrinkles, a luminous complexion, and a radiant, golden glow.

Recommended for Skin Instants© showing signs of epidermal aging, Le Grand Serum tones, revitalizes, and calms the epidermis while strengthening the skin's natural defense system. Its rich content in active ingredients delivers exceptional results, leaving the skin plumped up, toned, and luminous, with a brighter complexion and superior hydration.

Produced in limited batches during the winter, Le Grand Serum is a bestselling and highly specialized product from Biologique Recherche. Considered the flagship product of the brand, it is a heavenly addition to any skincare regimen, offering instant and exceptional results for revitalized, moisturized, and radiant skin.

Recommended For

All Skin Instants

How to Use

Deposit a few drops of Le Grand Serum in the hollow of your hand. Penetrate into skin by light massage over eyes, face, neck, and decollete morning and evening before and/or after moisturizer.  Le Grand Serum is a sublimating elixir, a genuine concentrate of beauty whose action grows more intense with each consecutive application.

Products we recommend to use with this amazing serum are:

Cleanser: Lait VIP 02, Lait EVEau Micellaire Biosensible

Exfoliant: P50T/P50 PIGM 400

Serums: Serum 3R (3 months on then off 3 months) and Serum A-Glyca

Biologique Recherche moisturizer of choice.

Finish off with Serum de Teint for that fabulous glow.


Amin Acids, Extracts of Elder, of Chestnut, of Tropical Almond and of Watercress,
Extract of Myrrh, Myrtle and Onion, Hexapeptides

Anti-Free radicals: Mimosa, Cranberry and Wasabi Extracts

Soothing: Kudzu Extract and Polysaccharides

Moisturizing: NMF, Hryaluronic Acid and Silk Extract

Toning: Extracts of Witch Hazel and St. John's Wort, Black Crowberry Juice

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